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1: Int J Sport Nutr Exerc Metab. 2007 Feb;17(1):92-108.Links
Eight weeks of aromatase inhibition using the nutritional supplement Novedex XT: effects in young, eugonadal men.Willoughby DS, Wilborn C, Taylor L, Campbell W.
Department of Health, Human Performance, and Recreation, Baylor University, Waco, TX 76798-7313, USA.
This study examined the effects of an aromatase-inhibiting nutritional supplement on serum steroid hormones, body composition, and clinical safety markers. Sixteen eugonadal young men ingested either Novedex XT or a placebo daily for 8 wk, followed by a 3-wk washout period. Body composition was assessed and blood and urine samples obtained at weeks 0, 4, 8, and 11. Data were analyzed by 2-way repeated-measures ANOVA. Novedex XT resulted in average increases of 283%, 625%, 566%, and 438% for total testosterone (P=0.001), free testosterone (P=0.001), dihydrotestosterone (P=0.001), and the testosterone:estrogen ratio (P=0.001), respectively, whereas fat mass decreased 3.5% (P=0.026) during supplementation
. No significant differences were observed in blood and urinary clinical safety markers or for any of the other serum hormones (P>0.05). This study indicates that Novedex XT significantly increases serum androgen levels and decreases fat mass.
PMID: 17460335 [PubMed - indexed for MEDLINE]